Detalhe da pesquisa
1.
Reactions of Plasmodium falciparum Ferredoxin:NADP+ Oxidoreductase with Redox Cycling Xenobiotics: A Mechanistic Study.
Int J Mol Sci
; 21(9)2020 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32370303
2.
Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1).
Int J Mol Sci
; 21(22)2020 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33228195
3.
Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity.
Int J Mol Sci
; 20(18)2019 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31533349
4.
Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase.
Molecules
; 24(24)2019 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31835450
5.
Mechanism of Two-/Four-Electron Reduction of Nitroaromatics by Oxygen-Insensitive Nitroreductases: The Role of a Non-Enzymatic Reduction Step.
Molecules
; 23(7)2018 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29987261
6.
Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma.
Biochim Biophys Acta
; 1864(2): 219-32, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26596252
7.
Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis.
Chem Res Toxicol
; 29(1): 26-39, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26630137
8.
Naphtho[1',2':4,5]imidazo[1,2-a]pyridine-5,6-diones: Synthesis, enzymatic reduction and cytotoxic activity.
Bioorg Med Chem Lett
; 26(2): 512-517, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681508
9.
The study of NADPH-dependent flavoenzyme-catalyzed reduction of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans).
Int J Mol Sci
; 15(12): 23307-31, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25517035
10.
Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro.
Front Pharmacol
; 14: 1193282, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37426813
11.
Quinone- and nitroreductase reactions of Thermotoga maritima peroxiredoxin-nitroreductase hybrid enzyme.
Arch Biochem Biophys
; 528(1): 50-6, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982531
12.
An Efficient Synthesis and Preliminary Investigation of Novel 1,3-Dihydro-2H-benzimidazol-2-one Nitro and Nitramino Derivatives.
Materials (Basel)
; 15(23)2022 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499818
13.
Investigation of oxygen influence to the optical properties of tirapazamine.
J Mol Model
; 28(4): 96, 2022 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320419
14.
Redox reactions of the FAD-containing apoptosis-inducing factor (AIF) with quinoidal xenobiotics: a mechanistic study.
Arch Biochem Biophys
; 512(2): 183-9, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21664341
15.
Benzimidazole Derivatives as Energetic Materials: A Theoretical Study.
Materials (Basel)
; 14(15)2021 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361305
16.
Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase.
Arch Biochem Biophys
; 494(1): 32-9, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19919822
17.
Role of single-electron oxidation potential and lipophilicity in the antiplasmodial in vitro activity of polyphenols: comparison to mammalian cells.
Z Naturforsch C J Biosci
; 63(5-6): 445-50, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18669034
18.
Two-electron reduction of quinones by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships.
Acta Biochim Pol
; 54(2): 379-85, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17546202
19.
Aziridinyl-substituted benzo-1,4-quinones: A preliminary investigation on the theoretical and experimental studies of their structure and spectroscopic properties.
Spectrochim Acta A Mol Biomol Spectrosc
; 178: 136-141, 2017 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28182983
20.
Modeling and investigation of new explosive materials based on N-(3,5-dimethyl-2,4,6-trinitrophenyl)-1H-1,2,4-triazol-3-amine.
J Mol Model
; 23(8): 228, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28717994